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GLP-1 Medications and Contraception
What You Should Know
5
Jun 2025
GLP-1 Medications and Contraception

As your local pharmacist, we're always here to provide guidance on how medications might affect your everyday life — especially when it comes to something as important as contraception. If you're taking, or thinking about taking, a GLP-1 medication for type 2 diabetes or weight loss, here’s what you need to know about how these medications could impact your contraception.


What Are GLP-1 Agonists?

GLP-1 agonists are a type of prescription medication that help:

  • Lower blood sugar

  • Suppress appetite

  • Slow down digestion (this is called delayed gastric emptying)

You might know them by brand names such as:

  • Ozempic, Wegovy, Rybelsus (semaglutide)

  • Mounjaro (tirzepatide)

  • Saxenda (liraglutide)

  • Trulicity (dulaglutide)

  • Bydureon (exenatide)

  • Suliqua (contains lixisenatide)

These are often used for managing type 2 diabetes or supporting weight loss.


Will GLP-1 Medications Affect My Contraceptive Pill?

That depends on which GLP-1 you're using:

Most GLP-1 medications (like semaglutide, liraglutide, dulaglutide)

There is currently no evidence that these affect how well your oral contraceptive (like the combined pill or mini pill) works.

⚠️ Tirzepatide (Mounjaro)

This one’s a little different. If you're taking tirzepatide, you should use extra contraception (e.g. condoms) for:

  • Four weeks after starting

  • Four weeks after any dose increase

Alternatively, you may want to switch to a non-oral method of contraception while on tirzepatide.


What If I’m Sick While Taking My Pill?

Side effects like diarrhoea or vomiting are fairly common with GLP-1 medications, especially in the beginning.

  • If you vomit within 3 hours of taking your pill, or have severe diarrhoea for more than 24 hours, your pill may not be absorbed properly.

  • In that case, follow the usual “missed pill” advice, and consider using condoms or switching to a non-oral contraceptive method if sickness continues.


Do GLP-1 Medications Affect Non-Oral Contraceptives?

Good news—they don’t.

If you use contraception that isn't taken by mouth (like the coil, implant, injection, patch or ring), there's no known interaction with GLP-1 medications. You don't need to take any extra precautions when using these methods.


Planning to Switch GLP-1 Medications?

If you're switching to tirzepatide from any other GLP-1 medication, the same advice applies: use condoms for four weeks after the switch, and again after any dose increases, while continuing with your pill. Or consider changing to a non-oral option.


What About Emergency Contraception?

We don’t yet know whether oral emergency contraception is affected by GLP-1 medications. If you need emergency contraception:

  • The copper coil (IUD) is the most reliable option and isn't affected by vomiting or diarrhoea.

  • Always tell your healthcare provider about all the medications you're taking, including GLP-1s.


Can I Take GLP-1 Medications If I'm Pregnant or Planning Pregnancy?

No—GLP-1 medications are not recommended in pregnancy. If you are planning to get pregnant, you should stop your GLP-1 in advance:

GLP-1 Medication Stop This Many Weeks Before Trying to Conceive
Tirzepatide 4 weeks
Semaglutide 8 weeks
Exenatide 12 weeks

If you find out you’re pregnant while on a GLP-1, speak to your GP or pharmacist right away.


Final Thoughts from Your Local Pharmacist

GLP-1 medications can be life-changing—but they do come with some important things to consider when it comes to contraception. If you're starting, switching, or currently using a GLP-1 and have any concerns about your birth control, don’t hesitate to talk to us.

✅ Always get your GLP-1 medication from a registered pharmacy to ensure it's safe and effective.

�� Need help or advice? We’re here to answer your questions—just give us a call or stop by for a chat.


If you would like to know if GLP1 medications are suitable for you, you can book a free appointment by completing our pre-screening  questionnaire below:


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